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Epitranscriptomic profiling of VSMC phenotypes reveals uridine modifications linked to post-transcriptional regulation

2025-12-22

Abstract excerpt

<h4>Background</h4> Vascular smooth muscle cells (VSMCs) phenotypic plasticity can modulate atherosclerosis progression. Although several gene regulatory steps towards pro-inflammatory phenotypes have been well-studied, epitranscriptomic changes during this transition and their regulatory roles remain unexplored. <h4>Methods and Results</h4> Primary human VSMCs stimulated with TGF-β1 to induce atheroprotective,...

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Literature Corpus work
cc2e2924-3311-5152-8771-a80834c0ef4e
DOI
10.64898/2025.12.19.694735
Open publication

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Epitranscriptomic profiling of VSMC phenotypes reveals uridine modifications linked to post-transcriptional regulationDOI 10.64898/2025.12.19.694735
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