Article

RegEnrich: An R package for gene regulator enrichment analysis reveals key role of ETS transcription factor family in interferon signaling

2021-01-26

Abstract excerpt

Changes in a few key transcriptional regulators can lead to different biological states, including cell activation and differentiation, and diseases. Extracting the key gene regulators governing a biological state allows us to gain mechanistic insights and can further help in translational research. Most current tools perform pathway/GO enrichment analysis to identify key genes and regulators but tend to overlook...

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Literature Corpus work: cbf8fdb9-6313-580a-9c7b-c53476f7b931
DOI: 10.1101/2021.01.24.428029

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