Article

SP1 Initiates Epithelial-Mesenchymal Transition of CTCs and Inhibits Metastasis in Prostate Cancer

2021-05-21

Abstract excerpt

<h4>Background: </h4> Circulating tumor cells （CTCs）are the basis of cancer metastasis. Till now, the role of different subtypes of CTCs in metastasis is unclear. <h4>Methods: </h4>: We used the Canpatrol TM technique to isolate CTCs from 102 prostate cancer (PCa) patients. The EMT markers of CTCs were detected by FISH and classified CTCs into Epethial (E-CTCs), Mesenchymal (M-CTCs) and Mesenchymal/Epethial-CTCs (...

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Literature Corpus work: cbf12016-2c01-5e50-a10d-370d47ad64d3
DOI: 10.21203/rs.3.rs-474528/v1

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