Article

CD117/c-kit Defines a Prostate CSC-Like Subpopulation Driving Progression and TKI Resistance

2018-04-23

Abstract excerpt

<h4>ABSTRACT</h4> Cancer stem-like cells (CSCs) are associated with cancer progression, metastasis, and recurrence, and may also represent a subset of circulating tumor cells (CTCs). In our prior study, CTCs in advanced prostate cancer patients were found to express CD117/c-kit in a liquid biopsy. Whether CD117 expression played an active or passive role in the aggressiveness and migration of these CTCs remained...

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Literature Corpus work: 53c008f2-4ffb-59c3-a8f7-1470ba8eb554
DOI: 10.1101/256107

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