Article

SPP1 Promotes Enzalutamide Resistance and EMT Activation in CRPC Progression via PI3K/AKT and ERK1/2 Pathways

2021-05-20

Abstract excerpt

The bottleneck arising from castration-resistant prostate cancer (CRPC) treatment is its high metastasis potential and anti-androgen drug resistance, which severely affects survival time of prostate cancer (PCa) patients. In our previous study, we firstly revealed SPP1 was a potential hub signature for predicting metastatic CRPC (mCRPC) development. Herein, we integrated multiple databases to explore the associati...

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Literature Corpus work: 217e95c2-d86a-5c98-8529-74ab47012434
DOI: 10.21203/rs.3.rs-533801/v1

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