Article

Protein degradation shapes developmental tempo in mouse and human neural progenitors

2024-08-01

Abstract excerpt

<h4>ABSTRACT</h4> The pace of embryonic development differs markedly across mammalian species, yet the molecular mechanisms underlying these tempo differences remain largely unknown. Here, we systematically compared protein dynamics in mouse and human neural progenitors (NPs) and examined how protein stability influences developmental timing. We find that mouse NPs exhibit faster protein production and degradatio...

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Literature Corpus work: cbeaaa2a-a9e3-5e18-8351-baf246730522
DOI: 10.1101/2024.08.01.604391

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