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CCR2 recruits monocytes to the lung, while CX3CR1 modulates positioning of monocyte-derived CD11c <sup>pos</sup> cells in the lymph node during pulmonary tuberculosis

2025-02-08

Abstract excerpt

<h4>ABSTRACT</h4> Infection by Mycobacterium tuberculosis (Mtb) continues to cause more than 1 million deaths annually, due to pathogen persistence in lung macrophages and dendritic cells derived from blood monocytes. While accumulation of monocyte-derived cells in the Mtb-infected lung partially depends on the chemokine receptor CCR2, the other chemoattractant receptors regulating trafficking remain undefined....

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Literature Corpus work
cbde5756-26bc-5deb-a5e3-d5f9f0147e93
DOI
10.1101/2025.02.07.637199
Open publication

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CCR2 recruits monocytes to the lung, while CX3CR1 modulates positioning of monocyte-derived CD11c <sup>pos</sup> cells in the lymph node during pulmonary tuberculosisDOI 10.1101/2025.02.07.637199
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