Article
Mycobacterium tuberculosis H37Rv Strain Increases the Frequency of CD3+TCR+ Macrophages and Affects Their Phenotype, but Not Their Migration Ability.
International journal of molecular sciences - 28 Dec 2021
Ramon-Luing Lucero A, Carranza Claudia, Téllez-Navarrete Norma A, Medina-Quero Karen, Gonzalez Yolanda, Torres Martha, Chavez-Galan Leslie
Abstract excerpt
In mycobacterial infections, the number of cells from two newly discovered subpopulations of CD3+ myeloid cells are increased at the infection site; one type expresses the T cell receptor (CD3+TCRαβ+) and the other does not (CD3+TCRαβ-). The role of Mycobacterium tuberculosis (Mtb) virulence in generating these subpopulations and the ability of these cells to migrate remains unclear. In this study,...
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