Article
Cutting Edge: Characterization of Human Tissue-Resident Memory T Cells at Different Infection Sites in Patients with Tuberculosis.
Journal of immunology (Baltimore, Md. : 1950) - 1 May 2020
Yang Qianting, Zhang Mingxia, Chen Qi, Chen Weixin, Wei Cailin, Qiao Kun, Ye Taosheng, Deng Guofang, Li Jin, Zhu Jialou, Cai Yi, Chen Xinchun, Ma Li
Abstract excerpt
Tissue-resident memory T cells (TRMs) have a key role in mediating the host defense against tuberculosis (TB) in mice, but their human counterparts have not been well characterized. In this article, we recruited patients with TB and determined TRM frequency, trafficking, activation marker expression, and cytokine production by flow or mass cytometry at different infection sites, including peripheral blood,...
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