Article

Profiling and Targeting of Regulatory RNAs to Upregulate Gene Expression

2026-04-23

Abstract excerpt

Transcription of long noncoding RNAs (lncRNAs), including enhancer RNAs (eRNAs) and promoter-associated RNAs (paRNAs), collectively termed regulatory RNAs (regRNAs), is a hallmark of active gene expression, yet it remains unknown whether regRNAs can be targeted to selectively enhance transcription in cis . We developed regRNA Capture-seq, a high-throughput method to profile regRNAs, and applied it to primary hum...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cbcefdc5-2871-53d0-b221-701484e27f02
DOI: 10.64898/2026.04.21.719874

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Profiling and Targeting of Regulatory RNAs to Upregulate Gene ExpressionDOI 10.64898/2026.04.21.719874Read

Genome-wide enhancer RNA profiling adds molecular links between genetic variation and human cancers.Semantic proximity Read

eRNA-IDO: a one-stop platform for identification, interactome discovery and functional annotation of enhancer RNAsSemantic proximity Read

Extensive genomic plasticity identified by anti-cancer Huaier therapySemantic proximity Read

Characterizing nascent transcription patterns of PROMPTs, eRNAs, and readthrough transcripts in the ENCODE4 deeply profiled cell linesSemantic proximity Read

Enhancer RNA transcriptome-wide association study reveals an atlas of pan-cancer susceptibility eRNAsSemantic proximity Read

Profiling of transcribed <i>cis</i> -regulatory elements in single cellsSemantic proximity Read

Cis-Regulatory Atlas in Primary Human CD4+ T CellsSemantic proximity Read

eRNA profiling uncovers the enhancer landscape of oesophageal adenocarcinoma and reveals new deregulated pathwaysSemantic proximity Read

Noncoding RNAs in chromatin organization and transcription regulation: an epigenetic view.Semantic proximity Read

HDI-STARR-seq Identifies Functional GH-regulated Sex-Biased Hepatocyte Enhancers Linked to Liver Metabolism and DiseaseSemantic proximity Read

lncRNA CHASERR Integrates Transcriptional and Post-Transcriptional Gene RegulationSemantic proximity Read

Multiple human enhancer RNAs contain long translated open reading framesSemantic proximity Read