Article

DNA energy constraints shape biological evolutionary trajectories

2019-05-03

Abstract excerpt

Most living systems rely on double-stranded DNA (dsDNA) to store their genetic information and perpetrate themselves. Thus, the biological information contained within a dsDNA molecule, in terms of a linear sequence of nucleotides, has been considered the main target of the evolution. However, in this information-centred perspective, certain DNA sequence symmetries are difficult to explain. Here we show that these...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cbc21353-8679-565d-a1da-86de4bd34141
DOI: 10.1101/625681

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

DNA energy constraints shape biological evolutionary trajectoriesDOI 10.1101/625681Read

Energy mapping of the genetic code and genomic domains: implications for code evolution and molecular Darwinism.Semantic proximity Read

The driving force behind genomic diversity.Semantic proximity Read

The fundamental tradeoff in genomes and proteomes of prokaryotes established by the genetic code, codon entropy, and physics of nucleic acids and proteins.Semantic proximity Read

Quantitative theory of entropic forces acting on constrained nucleotide sequences applied to virusesSemantic proximity Read

In pursuit of the framework behind the biosphere: S-curves, self-assembly and the genetic entropy paradox.Semantic proximity Read

Evolution of the highest fidelity DNA replication systemsSemantic proximity Read

The information continuum model of evolution.Semantic proximity Read

Codons support the maintenance of intrinsic DNA polymer flexibility over evolutionary timescales.Semantic proximity Read

Molecular systematic perspectives on biome origins and dynamics.Semantic proximity Read

Potential energy landscapes reveal the information-theoretic nature of the epigenomeSemantic proximity Read

Properties of a general model of DNA evolution under no-strand-bias conditions.Semantic proximity Read

Accurate estimations of evolutionary times in the context of strong CpG hypermutability.Semantic proximity Read