Article
Potential energy landscapes reveal the information-theoretic nature of the epigenome
2016-06-18
Abstract excerpt
<h4>ABSTRACT</h4> Epigenetics is defined as genomic modifications carrying information independent of DNA sequence heritable through cell division. In 1940, Waddington coined the term “epigenetic landscape” as a metaphor for pluripotency and differentiation, but epigenetic potential energy landscapes have not yet been rigorously defined. Using well-grounded biological assumptions and principles of statistical phy...
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Identifiers and source
- Literature Corpus work
- 50c6c04c-c9a9-512b-aa27-145adc3617ae
- DOI
- 10.1101/059766