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Energy mapping of the genetic code and genomic domains: implications for code evolution and molecular Darwinism.

Quarterly reviews of biophysics - 4 Nov 2020

Klump Horst H, Völker Jens, Breslauer Kenneth J

Abstract excerpt

When the iconic DNA genetic code is expressed in terms of energy differentials, one observes that information embedded in chemical sequences, including some biological outcomes, correlate with distinctive free energy profiles. Specifically, we find correlations between codon usage and codon free energy, suggestive of a thermodynamic selection for codon usage. We also find correlations between what are considered...

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PMID: 33143792
DOI: 10.1017/S0033583520000098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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