Article

MHC Attention: Identifying HLA-E presented cancer antigens through deep learning and high-throughput screening

2026-06-10

Abstract excerpt

HLA-E presented cancer peptides can be promising cancer therapy targets, as HLA-E is minimally polymorphic and widely expressed across human populations and cancer types. However, systematic discovery of cancer associated HLA-E peptides has been constrained by sparse training data and the technical difficulty of HLA-E immunopeptidomics. Here we develop an integrated HLA-E antigen discovery platform combining a dee...

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Literature Corpus work: cb9015b5-ab3a-561e-a65a-34f522a403f2
DOI: 10.64898/2026.06.08.730987

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