Article

Non-canonical endogenous expression of voltage-gated sodium channel NaV1.7 subtype by the TE671 rhabdomyosarcoma cell line

2024-01-31

Abstract excerpt

<h4>Background: </h4> and Purpose: The human TE671 cell line was originally used as a model of medulloblastoma but has since been reassigned as rhabdomyosarcoma. Despite the characterised endogenous expression of voltage-sensitive sodium currents in these cells, the specific voltage-gated sodium channel (VGSC) subtype underlying these currents remains unknown. Experimental Approach: To profile the VGSC subtype in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cb65bb32-9acd-5476-a8c9-d184197444c8
DOI: 10.22541/au.170666896.68088559/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Non-canonical endogenous expression of voltage-gated sodium channel NaV1.7 subtype by the TE671 rhabdomyosarcoma cell lineDOI 10.22541/au.170666896.68088559/v1Read

Towards development of Nav1.7 channel modulators for pain treatment: A comparison of mexiletine effect in two cell models by automated patch clampSemantic proximity Read

Cardiac sodium channels expressed in a peripheral neurotumor-derived cell line, RT4-B8.Semantic proximity Read

Tetrodotoxin-resistant Na+ channels in human neuroblastoma cells are encoded by new variants of Nav1.5/SCN5A.Semantic proximity Read

Novel mutations mapping to the fourth sodium channel domain of Nav1.7 result in variable clinical manifestations of primary erythromelalgia.Semantic proximity Read

Characterisation of Nav types endogenously expressed in human SH-SY5Y neuroblastoma cellsSemantic proximity Read

Differential gene expression profiles of two excitable rat cell lines after over-expression of WT- and C121W-β1 sodium channel subunits.Semantic proximity Read

Functional expression of voltage-gated sodium channels in human colorectal cancers in vitro : role in invasivenessSemantic proximity Read

Molecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus, heart, and testisSemantic proximity Read

A Novel SCN9A Mutation (F826Y) in Primary Erythromelalgia Alters the Excitability of Nav1.7.Semantic proximity Read

Voltage-gated sodium channels in the mammalian heartSemantic proximity Read

A single sodium channel mutation produces hyper- or hypoexcitability in different types of neurons.Semantic proximity Read

A sodium channel gene SCN9A polymorphism that increases nociceptor excitability.Semantic proximity Read