Cardiac sodium channels expressed in a peripheral neurotumor-derived cell line, RT4-B8.

doi:10.1152/ajpcell.1996.270.5.C1522

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Article

Cardiac sodium channels expressed in a peripheral neurotumor-derived cell line, RT4-B8.

The American journal of physiology - 1 May 1996

Zeng D, Kyle J W, Martin R L, Ambler K S, Hanck D A

Abstract excerpt

RT4-B is one of several cell lines derived from a multipotent stem cell line, RT4-AC, which originated from a rat peripheral neurotumor. Based on Northern blot and ribonuclease protection experiments, RT4-B8 cells have been proposed to express rat cardiac Na channel mRNA as the major isoform. We...

Topics

Animals
Blotting, Northern
Electrophysiology
Myocardium
Peripheral Nervous System Neoplasms
Phenotype
Polymerase Chain Reaction
Rats
Saxitoxin
Sodium Channels
Transcription, Genetic
Tumor Cells, Cultured

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