Article

Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer types

2017-09-03

Abstract excerpt

We present the most comprehensive catalogue of cancer-associated gene alterations through characterization of tumor transcriptomes from 1,188 donors of the Pan-Cancer Analysis of Whole Genomes project. Using matched whole-genome sequencing data, we attributed RNA alterations to germline and somatic DNA alterations, revealing likely genetic mechanisms. We identified 444 associations of gene expression with somatic...

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Literature Corpus work: cb642baf-5fc7-593a-bd96-df132b4c2ef3
DOI: 10.1101/183889

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