Article

Biophysical basis of alpha rhythm disruption in Alzheimer’s disease

2018-05-31

Abstract excerpt

Alpha is one of the most prominent rhythms (7.5–12.5 Hz) detected in electroencephalography (EEG) during wakeful relaxation with closed eyes. In response to elevated ambient acetylcholine levels, a subclass of thalamic pacemaker cells generate alpha. This rhythm is intrinsic to the cell and is robustly orchestrated by an interplay of hyperpolarization activated cyclic nucleotide gated channels(HCN) and calcium-ion...

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Literature Corpus work: cb2aecf0-a1ba-5972-ad4b-73f1b66b9f14
DOI: 10.1101/335471

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