Article
SPARC Accelerates Biliary Tract Cancer Progression through CTGF-mediated Tumor-Stroma interactions: SPARC as a Prognostic Marker of Survival after Neoadjuvant Therapy
2023-01-20
Abstract excerpt
<h4>Purpose: </h4> In biliary tract cancer (BTC), malignancy is strongest at the invasion front. To improve the BTC prognosis, the invasion front should be controlled. We evaluated tumor-stroma crosstalk at the tumor center and at the invasion front of BTC lesions. We investigated the expression of SPARC, a marker of cancer-associated fibroblasts, and determined its ability to predict BTC prognosis after neoadjuva...
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Identifiers and source
- Literature Corpus work
- cb24b49a-aefa-5914-a225-0a0567160f75
- DOI
- 10.21203/rs.3.rs-2487774/v1
