Article

Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients

2021-06-30

Abstract excerpt

Progression to metastatic disease remains the main cause of cancer death. Yet, the underlying genomic mechanisms driving metastasis remain largely unknown. Here, we present MSK-MET, an integrated pan-cancer cohort of tumor genomic and clinical outcome data from more than 25,000 patients. We analyzed this dataset to identify associations between tumor genomic alterations and patterns of metastatic dissemination acr...

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Literature Corpus work: cb04ee5d-b509-53dd-be9f-289c0793e24b
DOI: 10.1101/2021.06.28.450217

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