Article

Myocardial <i>Notch-Rbpj</i> deletion does not affect heart development or function

2018-08-16

Abstract excerpt

During vertebrate cardiac development NOTCH signaling activity in the endocardium is essential for the crosstalk between endocardium and myocardium that initiates ventricular trabeculation and valve primordium formation. This crosstalk leads later to the maturation and compaction of the ventricular chambers and the morphogenesis of the cardiac valves, and its alteration may lead to disease. Although endocardial NO...

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Literature Corpus work: caf871fe-9415-587d-aa74-55236fd61730
DOI: 10.1101/393348

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