Article

Recurrent <i>PD-L1</i> Structural Rearrangements in Natural Killer/T Cell Lymphoma Patients with Complete Response to PD-1 Blockade Therapy

2018-07-19

Abstract excerpt

<h4>Abstract:</h4> This study aims to identify recurrent genetic alterations in relapsed or refractory (RR) natural-killer/T-cell lymphoma (NKTL) patients who have achieved complete response (CR) with programmed cell death 1 (PD-1) blockade therapy. Seven of the eleven patients treated with pembrolizumab achieved CR while the remaining four had progressive disease (PD). Using whole genome sequencing (WGS), we fou...

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Literature Corpus work: caf23249-aaac-5042-92d9-43708687bddb
DOI: 10.1101/372383

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