Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MYD88 L265P mutation and CDKN2A loss are early mutational events in primary central nervous system diffuse large B-cell lymphomas

5 Feb 2019

Abstract excerpt

Abstract The genetic alterations that define primary central nervous system lymphoma (PCNSL) are incompletely elucidated, and the genomic evolution from diagnosis to relapse is poorly understood. We performed whole-exome sequencing (WES) on 36 PCNSL patients and targeted MYD88 sequencing on a validation cohort of 27 PCNSL patients. We also performed WES and phylogenetic analysis of 3 matched newly diagnosed and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CNS Lymphoma Diagnosis and Treatment
Share to Glioma Diagnosis and Treatment
Share to Lymphoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30723112
DOI: 10.1182/bloodadvances.2018027672

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MYD88 L265P mutation and CDKN2A loss are early mutational events in primary central nervous system diffuse large B-cell lymphomasPMID 30723112Read ↗

Characterization of genomic alterations in primary central nervous system lymphomas.Semantic proximity Read ↗

Mutational analysis of primary central nervous system lymphoma.Semantic proximity Read ↗

Genomic characterization of primary central nervous system lymphoma.Semantic proximity Read ↗

Genome-Wide Analysis Uncovers Novel Recurrent Alterations in Primary Central Nervous System Lymphomas.Semantic proximity Read ↗

Comparative Study on the Clinicopathologic and Molecular Characteristics of Primary and Secondary Diffuse Large B-cell Lymphoma in the Central Nervous System.Semantic proximity Read ↗

Primary CNS lymphoma commonly expresses immune response biomarkersSemantic proximity Read ↗

The genomic and transcriptional landscape of primary central nervous system lymphomaSemantic proximity Read ↗

Recurrent mutations of MYD88 and TBL1XR1 in primary central nervous system lymphomas.Semantic proximity Read ↗

Whole-Genome/Exome Sequencing Uncovers Mutations and Copy Number Variations in Primary Diffuse Large B-Cell Lymphoma of the Central Nervous SystemSemantic proximity Read ↗

Clinicopathologic correlates of MYD88 L265P mutation and programmed cell death (PD-1) pathway in primary central nervous system lymphomaSemantic proximity Read ↗

Targetable genetic features of primary testicular and primary central nervous system lymphomasSemantic proximity Read ↗

Recurrent mutations of CD79B and MYD88 are the hallmark of primary central nervous system lymphomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.