Article
Recurrent Mutations in Refractory/Relapsed Diffuse Large B-Cell Lymphoma by Targeted Gene Sequencing.
Cytogenetic and genome research - 1 Jan 2023
Sharma Aditi, Das Ashim, Bal Amanjit, Srinivasan Radhika, Malhotra Pankaj, Prakash Gaurav, Kumar Rajender
Abstract excerpt
INTRODUCTION: Whole-genome sequencing of diffuse large B-cell lymphoma (DLBCL) has identified recurrent mutations involved in pathogenesis and potentially affecting response to therapy. In this pilot study, a targeted gene panel was created to identify mutations associated with relapse/refractoriness. MATERIAL AND METHODS: A 14-gene targeted panel was designed to sequence thirteen patients who were in remission...
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