Article

Cyclic stretching induces maturation of human induced pluripotent stem cell-derived cardiomyocytes through nuclear mechanotransduction

2024-01-31

Abstract excerpt

During cardiogenesis, cardiac cells receive various stimuli, such as biomechanical and chemical cues, from the surrounding microenvironment, and these signals induce the maturation of heart cells. Mechanical force, especially tensile force in the heart, is one of the key stimuli that induce cardiomyocyte (CM) maturation through mechanotransduction, a process through which physical cues are transformed into biologi...

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Literature Corpus work: caeb9b7b-6578-5b52-b20c-883c01261fa8
DOI: 10.22541/au.170668502.25758939/v1

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