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Bioengineering Approaches to Mature Human Pluripotent Stem Cell-Derived Cardiomyocytes

9 Mar 2017

Abstract excerpt

Human pluripotent stem cell-derived cardiomyocytes (hPSC-CM) represent a potential unlimited cell supply for cardiac tissue engineering and possibly regenerative medicine applications. However, hPSC-CMs produced by current protocols are not representative of native adult human cardiomyocytes as they display immature gene expression profile, structure and function. In order to improve hPSC-CM maturity and...

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PMID: 28337437
DOI: 10.3389/fcell.2017.00019

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