Article

Effect of mechanical stretching stimulation on maturation of human iPS cell-derived cardiomyocytes co-cultured with human gingival fibroblasts

2023-12-16

Abstract excerpt

In the realm of regenerative medicine, despite the various techniques available for inducing the differentiation of induced pluripotent stem (iPS) cells into cardiomyocytes, there remains a need to enhance the efficiency of this induction process. This study aimed to improve the differentiation efficiency of iPS-derived cardiomyocytes (iPS-CMs) by incorporating mechanical stretching. Human iPS cells were co-cultur...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cbe28d14-be17-502d-8bf4-774f891f7d4c
DOI: 10.1101/2023.12.15.567696

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Effect of mechanical stretching stimulation on maturation of human iPS cell-derived cardiomyocytes co-cultured with human gingival fibroblastsDOI 10.1101/2023.12.15.567696Read

Effect of mechanical stretching stimulation on maturation of human iPS cell-derived cardiomyocytes co-cultured with human gingival fibroblastsSemantic proximity Read

Cyclic stretching induces maturation of human induced pluripotent stem cell-derived cardiomyocytes through nuclear mechanotransductionSemantic proximity Read

Advancements in cardiac regenerative therapy: Scalable human iPSC-derived cardiomyocyte differentiation and maturationSemantic proximity Read

Engineering human pluripotent stem cells into a functional skeletal muscle tissueSemantic proximity Read

Progressive developmental cues from multiple cardiac cell types promote cardiomyocyte maturationSemantic proximity Read

Simple and efficient differentiation of human iPSCs into contractible skeletal muscles for muscular disease modelingSemantic proximity Read

Aligned nanofiber scaffolds improve functionality of cardiomyocytes differentiated from human induced pluripotent stem cell-derived cardiac progenitor cellsSemantic proximity Read

Physical developmental cues for the maturation of human pluripotent stem cell-derived cardiomyocytesSemantic proximity Read

Bioengineering Approaches to Mature Human Pluripotent Stem Cell-Derived CardiomyocytesSemantic proximity Read

Functional comparison of beating cardiomyocytes differentiated from umbilical cord‐derived mesenchymal/stromal stem cells and human foreskin‐derived induced pluripotent stem cellsSemantic proximity Read

ERRγ agonist under mechanical stretching manifests hypertrophic cardiomyopathy phenotypes of engineered cardiac tissue through maturation.Semantic proximity Read

Mechanical Stress Promotes Maturation of Human Myocardium From Pluripotent Stem Cell-Derived ProgenitorsSemantic proximity Read