Article

Plasma Oxylipin Profiling by High Resolution Mass Spectrometry Reveal Signatures of Inflammation and Hypermetabolism in Amyotrophic Lateral Sclerosis

2023-07-07

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized not only by progressive loss of motor neurons, but also linked to systemic hypermetabolism, oxidative stress, and inflammation. In this context, oxylipins have been investigated as signaling molecules linked to neurodegeneration. However, the nature and role of major oxylipins involved in ALS disease progression remain unclear. Import...

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Literature Corpus work: cae8dfc2-1626-5d6c-8b7d-cce623e744d4
DOI: 10.1101/2023.07.07.547101

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