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Article

High-Throughput Microbore LC-MS Lipidomics to Investigate APOE Phenotypes.

Analytical chemistry - 9 Jan 2024

Gadara Darshak, Berka Vratislav, Spacil Zdenek

Abstract excerpt

Microflow liquid chromatography interfaced with mass spectrometry (μLC-MS/MS) is increasingly applied for high-throughput profiling of biological samples and has been proven to have an acceptable trade-off between sensitivity and reproducibility. However, lipidomics applications are scarce. We optimized a μLC-MS/MS system utilizing a 1 mm inner diameter × 100 mm column coupled to a triple quadrupole mass...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38113351
DOI: 10.1021/acs.analchem.3c02652
PMCID: PMC10782415

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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