Article
[The role of lipids in the pathogenesis of lateral amyotrophic sclerosis].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2020
Alessenko A V, Gutner U A, Nebogatikov V O, Shupik M A, Ustyugov A A
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease characterized by selective degeneration of motor neurons of the motor cortex, brain stem and brain stem. Mutations in genes coding for SOD1, C9ORF72, TDP-43, FUS and others are associated with ALS and result in abnormal processing and transport of RNA as well as changes in the dynamics of cytoskeleton. In addition, a sharp change in the...
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