Unveiling amyotrophic lateral sclerosis complexity: insights from proteomics, metabolomics, and microbiomics

Abstract excerpt

Abstract Amyotrophic lateral sclerosis is the most common motor neuron disease and manifests as a clinically and genetically heterogeneous neurodegenerative disorder mainly affecting the motor systems. To date, despite promising results and accumulating knowledge on the pathomechanisms of amyotrophic lateral sclerosis, a specific disease-modifying treatment is still not available. In vitro and in vivo disease...

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