Personalized analysis of minimal residual cancer cells in peritoneal lavage fluid predicts peritoneal dissemination of gastric cancer

Abstract excerpt

<title>Abstract</title> <p>Peritoneal dissemination (PD) is the major type of gastric cancer (GC) recurrence and leads to rapid death. Current approach cannot precisely determine which patients are at high risk of PD. In this study, we developed a technology to detect minimal residual cancer cells in peritoneal lavage fluid (PLF) samples by parallel profiling tumor-specific mutations. We applied the technology to...

Topics

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• Clonal Evolution
• Gene Expression Profiling
• Gene Expression Regulation, Neoplastic
• Mutation
• Peritoneal Neoplasms
• Stomach Neoplasms
• Transcriptome
• Tumor Microenvironment

Identifiers and source

Literature Corpus work

cad422d4-7941-55bb-8728-19611232dbef

DOI

10.21203/rs.3.rs-275520/v1