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Liquid Biopsy in Gastric Cancer: Analysis of Somatic Cancer Tissue Mutations in Plasma Cell-Free DNA for Predicting Disease State and Patient Survival.

Clinical and translational gastroenterology - 24 Sept 2021

Varkalaite Greta, Forster Michael, Franke Andre, Kupcinskas Juozas, Skieceviciene Jurgita

Abstract excerpt

INTRODUCTION: Gastric cancer (GC) diagnosis in late stages and high mortality rates are the main issues that require new noninvasive molecular tools. We aimed to assess somatic mutational profiles in GC tissue and plasma cell-free DNA (cfDNA), evaluate their concordance rate, and analyze the role of multilayer molecular profiling to predict disease state and prognosis. METHODS: Treatment-naive GC patient group (n...

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Share to Antigens, Tumor-Associated, Carbohydrate
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34644276
DOI: 10.14309/ctg.0000000000000403
PMCID: PMC8462609

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