Article

Pan-Viral Conformational Landscapes of Frameshifting Elements Reveal Length-Dependent Plasticity and Antisense-Driven Structural Reprogramming

2026-05-15

Abstract excerpt

Programmed ribosomal frameshifting (PRF) is an essential strategy used by many RNA viruses to expand their coding capacity within compact genomes. This process is governed by frameshifting elements (FSEs), specialized RNA structures that regulate translation through dynamic secondary and tertiary conformations. While the structural adaptability of the SARS-CoV-2 FSE has been extensively characterized, the conforma...

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Literature Corpus work: 9c40e22a-802f-517e-b9ca-229b4bbe34d0
DOI: 10.64898/2026.05.13.724818

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