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Article

The Pancreatic Tumor Microenvironment Compensates for Loss of GOT2

2020-08-07

Abstract excerpt

<h4>ABSTRACT</h4> The tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDA) restricts vascularization and, consequently, access to blood-derived nutrients and oxygen, which impacts tumor growth. Intracellular redox imbalance is another restraint on cellular proliferation, yet it is unknown if the TME contributes to the maintenance of redox homeostasis in PDA cells. Here, we demonstrate that the l...

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Literature Corpus work
cac026d0-ed25-5eb3-b75e-b427d8a3ff00
DOI
10.1101/2020.08.07.238766
Open publication

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The Pancreatic Tumor Microenvironment Compensates for Loss of GOT2DOI 10.1101/2020.08.07.238766
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