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Pancreatic Cancer Metabolism: Breaking It Down to Build It Back Up

4 Nov 2015

Abstract excerpt

UNLABELLED: How do cancer cells escape tightly controlled regulatory circuits that link their proliferation to extracellular nutrient cues? An emerging theme in cancer biology is the hijacking of normal stress response mechanisms to enable growth even when nutrients are limiting. Pancreatic ductal adenocarcinoma (PDA) is the quintessential aggressive malignancy that thrives in nutrient-poor, hypoxic environments....

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PMID: 26534901
DOI: 10.1158/2159-8290.cd-15-0671

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