Vestibular migraine as a vestibulo-trigeminal interface phenotype: a triangulation study across genetics, peripheral multiomics and human cell atlases

Abstract excerpt

<title>Abstract</title> <p>Background Vestibular migraine (VM) is clinically established, but the biological problem is narrower and harder: whether VM has its own causal architecture or instead reflects migraine liability that is preferentially expressed through vestibular systems. We tested the latter possibility by asking whether migraine-vertigo overlap converges on vestibular and trigeminal programs. Method...

Topics

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• Gene Regulatory Networks
• Genome-Wide Association Study
• Migraine Disorders
• Multiomics
• Quantitative Trait Loci
• Single-Cell Analysis
• T-Lymphocytes, Regulatory
• Transcriptome

Identifiers and source

Literature Corpus work

ca97ea80-39e2-5081-8078-e8514c4e3806

DOI

10.21203/rs.3.rs-9347560/v1