Article
A genome-wide association study identifies novel loci of vertigo in an Asian population-based cohort.
Communications biology - 22 Aug 2024
Chen Shih-Pin, Hsu Chia-Lin, Chen Ting-Huei, Pan Li-Ling Hope, Wang Yen-Feng, Ling Yu-Hsiang, Chang Hsueh-Chen, Chen Yi-Ming, Fann Cathy Shen-Jang, Wang Shuu-Jiun
Abstract excerpt
The contributing genetic factors of vertigo remain poorly characterized, particularly in individuals of non-European ancestries. Here we show the genetic landscape of vertigo in an Asian population-based cohort. In a two-stage genome-wide association study (Ncase = 6199; Ncontrol = 54,587), we identify vertigo-associated genomic loci in DROSHA and ZNF91/LINC01224, with the latter replicating the findings in...
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