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Article

Dissecting the shared genetic architecture between migraine subtypes and cardiovascular diseases: a multi-layered genomic analysis.

The journal of headache and pain - 25 Jun 2026

Liu Yiming, Ma You, Liu Yiwei

Abstract excerpt

BACKGROUND: Epidemiological studies have linked migraine to an increased risk of cardiovascular disease (CVD); however, the shared genetic basis and putative causal relationships between migraine subtypes and cardiovascular traits remain poorly understood. METHODS: Leveraging large-scale GWAS summary statistics for migraine phenotypes (overall migraine, migraine with aura [MA], and migraine without aura [MO])...

Read the complete abstract on PubMed

Topics

Humans
Cardiovascular Diseases
Genome-Wide Association Study
Migraine Disorders
Genetic Predisposition to Disease
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genomics

Source

Open in PubMed Open full text

Identifiers

PMID: 42350979
DOI: 10.1186/s10194-026-02433-9
PMCID: PMC13560339

Genes

CAD
PHACTR1
ABO
FHOD3
LRP1
MEI1
SOX7
XKR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

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