Article

Phytochemical Modulation of Astrocyte A1/A2 Polarization and Hepcidin-Associated Iron Dysregulation in LPS-Driven Neuroinflammation

2026-05-18

Abstract excerpt

<h4>Background/Objectives</h4> Neuroinflammation-driven iron dysregulation and neurotoxic astrocyte polarization are increasingly recognized as interconnected pathological mechanisms in neurodegenerative diseases. Systemic inflammation triggered by strenuous exercise or infection can engage the central nervous system and astrocytic inflammatory responses and perturb iron homeostasis; however, targeted nutritional...

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Literature Corpus work: ca67034e-b70b-5293-a61c-b14f2f931ffd
DOI: 10.64898/2026.05.14.725062

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