Article

Plant extracts and omega-3 supplementation modulate hippocampal oxylipin profile in response to LPS-induced neuroinflammation

2024-09-12

Abstract excerpt

<title>Abstract</title> <p>Neuroinflammation is a critical protective mechanism in healthy humans but can become harmful if chronic and/or unregulated, leading to neuronal damage and cognitive alterations. Microglia, which regulate inflammation in the brain, become dysfunctional with age, producing proinflammatory cytokines and contributing to chronic low-grade neuroinflammation. Oxylipins, which are lipid mediat...

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Literature Corpus work: 64958cfc-e0bb-5b56-aad6-10a0a713c21e
DOI: 10.21203/rs.3.rs-4914707/v1

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