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Lung mesenchymal cell diversity rapidly increases at birth and is profoundly altered by hyperoxia

2021-05-20

Abstract excerpt

Lung mesenchymal cells play an essential role in development and at birth, as the lung moves from a fluid-filled to an oxygen-rich environment with a stable gas-liquid interface. The molecular details and cellular changes accompanying this highly coordinated process remain incompletely understood. Therefore, we performed single cell transcriptomics and in-situ imaging of the developing lung in both health and dise...

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Literature Corpus work
ca35eb60-0b29-57a9-9d0e-3291cac6b1a2
DOI
10.1101/2021.05.19.444776
Open publication

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Lung mesenchymal cell diversity rapidly increases at birth and is profoundly altered by hyperoxiaDOI 10.1101/2021.05.19.444776
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