Article

Clinical Interventions and Inflammatory Signaling Shape the Transcriptional and Cellular Architecture of the Early Postnatal Lung

2025-10-17

Abstract excerpt

<h4>ABSTRACT</h4> The early postnatal period in human development is characterized by extensive remodeling of the distal lung to support gas exchange, but this critical period remains poorly understood. Here, we constructed a comprehensive cellular atlas of the early postnatal human lung (0 to 2 years) using single-nucleus RNA sequencing of histologically normal specimens from 23 individuals. Our analysis identif...

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Literature Corpus work: 14ee3362-580b-501c-8a5c-47bba9ce3f13
DOI: 10.1101/2025.10.17.683116

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