Article

Transcriptional response of <i>Streptomyces coelicolor</i> to rapid chromosome relaxation or long-term supercoiling imbalance

2019-04-09

Abstract excerpt

<h4>ABSTRACT</h4> Negative DNA supercoiling allows chromosome condensation within a cell and facilitates DNA unwinding, which is required for the occurrence of DNA transaction processes, i.e., DNA replication, transcription and recombination. In bacteria, changes in chromosome supercoiling impact global gene expression; however, the limited studies on the global transcriptional response have focused mostly on pat...

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Literature Corpus work: ca0dd3df-e10b-53f8-8382-68abb7bd933e
DOI: 10.1101/602359

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