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Conjugation mediates large-scale chromosomal transfer in <i>Streptomyces</i> driving diversification of antibiotic biosynthetic gene clusters

2024-05-27

Abstract excerpt

Streptomyces are ubiquitous soil dwelling bacteria of special importance as a source of metabolites used in human and veterinary medicine, agronomy and industry. Conjugation is the main mechanism of Streptomyces Horizontal Gene Transfer, and this process has long been known to be accompanied by mobilization of chromosomal DNA. However, the magnitude of DNA transfer, or the localization of acquired DNA across thei...

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Literature Corpus work
e9f48d96-7c85-5fb8-bb3e-22e15015fbc8
DOI
10.1101/2024.05.27.596038
Open publication

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Conjugation mediates large-scale chromosomal transfer in <i>Streptomyces</i> driving diversification of antibiotic biosynthetic gene clustersDOI 10.1101/2024.05.27.596038
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