Article

Relative adrenal insufficiency is a risk factor and an endotype of sepsis - A proof of concept study to support a precision medicine approach for glucocorticoid sepsis therapy

2020-04-18

Abstract excerpt

<h4>Rational</h4> 25-60% of septic patients experience relative adrenal insufficiency (RAI) and glucocorticoid (GC) is frequently used in septic patients. However, the efficacy of GC therapy and whether the GC therapy should be based on the status of RAI are highly controversial. Critical barriers include technical limitations in properly identifying RAI in septic patients and a lack of RAI animal model. <h4>Obje...

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Literature Corpus work: ca0c3cf0-d155-5188-b9aa-2bde3bd05c4d
DOI: 10.1101/2020.04.16.043976

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