Article

Renoprotective Effects of Montelukast in Sepsis-Induced AKI: Targeting the NF-κB Pathway

2026-04-17

Abstract excerpt

<h4>Background: </h4> Sepsis-associated acute kidney injury (SA-AKI) is ubiquitous among patients with critical conditions and contributes to high mortality rates. Experimentally, SA-AKI was elicited in murine models via cecal ligation and puncture (CLP) technique. Aims This study aimed to determine the possible protective effects of montelukast on sepsis-induced acute kidney injury in a mouse sepsis model. Method...

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Literature Corpus work: 2ed1c065-02a8-513d-bef6-c5ae32f164a4
DOI: 10.12688/f1000research.163164.2

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