Article
Panel-Wide Screening of Tumour Cells of Diverse Histogenesis for Responsiveness to Silencing of miR-21, miR-17, and miR-155 by Mesyl Phosphoramidate Antisense Oligonucleotides
2026-05-22
Abstract excerpt
Molecular heterogeneity of malignant tumours remains a central challenge in oncology. Although neoplasms of distinct histogenesis share core oncogenic properties, the signaling networks sustaining these phenotypes are tumour-specific, highlighting the need for regulatory-level therapeutics adaptable to distinct molecular contexts. Oncogenic microRNAs (miRNAs), among which miR-21, miR-17, and miR-155 are broadly ov...
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Identifiers and source
- Literature Corpus work
- ca0851d5-f787-5ac3-9e4e-10f74705e205
- DOI
- 10.20944/preprints202605.1471.v1
