Article

A high-content screen profiles cytotoxic microRNAs in pediatric and adult glioblastoma cells and identifies miR-1300 as a potent inducer of cytokinesis failure

2019-10-01

Abstract excerpt

<h4>Background</h4> MicroRNAs play an important role in the regulation of mRNA translation, and have therapeutic potential in cancer and other diseases. <h4>Methods</h4> To profile the landscape of microRNAs with significant cytotoxicity in the context of glioblastoma (GBM), we performed a high-throughput screen using a synthetic oligonucleotide library representing all known human microRNAs in adult and pediatr...

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Literature Corpus work: c88651fa-e35e-52b4-a336-fe02ff9b17e7
DOI: 10.1101/789438

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