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Article

Tumor-specific polycistronic miRNA delivered by engineered exosomes for the treatment of glioblastoma

17 Oct 2023

Abstract excerpt

BACKGROUND: Glioblastoma (GBM) has poor prognosis due to ineffective agents and poor delivery methods. MicroRNAs (miRs) have been explored as novel therapeutics for GBM, but the optimal miRs and the ideal delivery strategy remain unresolved. In this study, we sought to identify the most effective pan-subtype anti-GBM miRs and to develop an improved delivery system for these miRs. METHODS: We conducted an unbiased...

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PMID: 37847405
DOI: 10.1093/neuonc/noad199

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